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Oxidative Stress

What Is Oxidative Stress and Why Does It Matter

8 April 202624 March 2026 by Matt Elliott
Illustration of oxidative stress and free radical damage to a cell

In 1991, Helmut Sies published a paper that gave a name to something biologists had been circling for years. He defined oxidative stress as an imbalance between the production of reactive oxygen species and the biological capacity to detoxify them or repair the resulting damage. The definition was precise enough to be useful and broad … Read more

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