How Your Body Makes Glutathione: The Synthesis Pathway

Illustration of the glutathione synthesis pathway inside a cell

If glutathione is the master antioxidant, then understanding how your body actually makes it is essential knowledge. The synthesis pathway reveals why oral glutathione supplements are largely ineffective, why certain nutrients and lifestyle factors matter so much and why the NRF2 pathway sits at the centre of your body’s antioxidant defence strategy. The Two Step … Read more

What Is Glutathione and Why Is It Called the Master Antioxidant

Illustration of glutathione molecule protecting a cell

In 1888, a French chemist named J. de Rey-Pailhade noticed that a substance in yeast cells could react with elemental sulphur. He named it philothion, from the Greek for sulphur-loving, and published a short paper describing its properties. The compound did not receive a proper chemical characterisation for another forty years. When it did, the … Read more