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NRF2 Pathway

The NRF2 Pathway: Why Scientists Call It the Master Switch

8 April 202624 March 2026 by Matt Elliott
Illustration of the NRF2 pathway activating protective genes inside a cell

In 1994, a team of researchers studying a protein involved in red blood cell development stumbled onto something larger than they were looking for. The protein, which they named NRF2, turned out to regulate not just one or two protective genes but hundreds of them. It sat at the top of the cell’s defence hierarchy, … Read more

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